IMAC-μSphere                                   

This is an affinity purification matrix for His-Tag Fusion proteins and other metal proteins.
polymer μSphere-based chromatographic matrix High Flow Rate，High capacity and high performance 

IMAC μSphere 6 cess IMAC medium, designed for purifying proteins and peptides that have an affinity for metal ions, such as histidine-tagged proteins but also untagged recombinant or native proteins

l         Uncharged IMAC resin allowing possibility to charge with your metal ion of choice for optimized selectivity

l         Convenient purification of histidine-tagged proteins, also when Ni2+ is not the best choice of metal ion

l         As BioProcess medium it fulfills industrial demands for security of supply, robust performance and regulatory support.

l         Available in the convenient and time-saving prepacked HiTrap and HiPrep formats.

IMAC μSphere 6 is a member of the range of IMAC chromatography media for capture and intermediate purification.

IMAC μSphere 6 is composed of highly cross-linked beads modified with a novel chelating ligand immobilized to the base matrix. IMAC μSphere 6 is supplied free of metal ions, allowing the user to charge it with the most appropriate metal ion for purification of a target protein.

The coupling chemistry and the novel ligand is designed to give minimal ligand leakage while providing high capacity.

IMAC μSphere 6 is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. 
As member of the BioProcess media range, IMAC μSphere 6 meets industrial demands with security of supply and comprehensive technical and regulatory support

Appendix:

Summary and Comparison of Matrices  Extensively and Successfully Used in Protein Purification and Analysis